CODE EXAMPLE FOR PYTHON

spread in python

#df = df[['gene_symbol', 'sample_id', 'fc']]
df = df.pivot(index='gene_symbol',columns='sample_id',values='fc')
print (df)
sample_id       S1     S2
gene_symbol              
a            100.0    1.3
b            100.0   14.0
c            112.0  125.0