import xlwt
from tempfile import TemporaryFile
book = xlwt.Workbook()
sheet1 = book.add_sheet('sheet1')
supersecretdata = [34,123,4,1234,12,34,12,41,234,123,3,56]
for i,e in enumerate(supersecretdata):
sheet1.write(i,1,e)
name = "random.xls"
book.save(name)
book.save(TemporaryFile())