# Python 2.x
import urllib
params = urllib.quote_plus("DRIVER={SQL Server Native Client 10.0};SERVER=dagger;DATABASE=test;UID=user;PWD=password")
engine = create_engine("mssql+pyodbc:///?odbc_connect=%s" % params)
# Python 3.x
import urllib
params = urllib.parse.quote_plus("DRIVER={SQL Server Native Client 10.0};SERVER=dagger;DATABASE=test;UID=user;PWD=password")
engine = create_engine("mssql+pyodbc:///?odbc_connect=%s" % params)
# using the above logic I just did the following
params = urllib.parse.quote_plus('DRIVER={SQL Server};SERVER=HARRISONS-THINK;DATABASE=LendApp;Trusted_Connection=yes;')
app.config['SQLALCHEMY_DATABASE_URI'] = "mssql+pyodbc:///?odbc_connect=%s" % params