IF EXISTS(SELECT * FROM INFORMATION_SCHEMA.COLUMNS WHERE TABLE_NAME = 'X' AND COLUMN_NAME = 'Y')
AND EXISTS(SELECT * FROM INFORMATION_SCHEMA.COLUMNS WHERE TABLE_NAME = 'Z' AND COLUMN_NAME = 'A')
BEGIN
UPDATE [dbo].[X]
SET Y= (SELECT inst.[A] FROM [dbo].[Z] s WHERE s.[B] = [dbo].[x].[B]);
END
GO