// street & city must be separated by ',' or '.'
const addressStr = '123 Main St., New York, NY 10001, USA';
const street = addressStr
.match(/(w+s[A-z]+.?s?)+(?=(,s([A-z]+s?)+,s[A-Z]{2}sd{5}))/g)
.toString();
console.log(street);
// 123 Main St.