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pandas drop unnamed columns

df = df.loc[:, ~df.columns.str.contains('^Unnamed')]

In [162]: df
Out[162]:
   colA  ColB  colC  colD  colE  colF  colG
0    44    45    26    26    40    26    46
1    47    16    38    47    48    22    37
2    19    28    36    18    40    18    46
3    50    14    12    33    12    44    23
4    39    47    16    42    33    48    38
Comment

drop all unnamed columns pandas

df.drop(df.columns[df.columns.str.contains('unnamed',case = False)],axis = 1, inplace = True)
Comment

remove unnamed columns pandas

df2.columns.str.match("Unnamed")
df2.loc[:,~df2.columns.str.match("Unnamed")]
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