import numpy as np A = np.array([[1, 4, 5, 12], [-5, 8, 9, 0], [-6, 7, 11, 19]]) print("A[:,0] =",A[:,0]) # First Column print("A[:,3] =", A[:,3]) # Fourth Column print("A[:,-1] =", A[:,-1]) # Last Column (4th column in this case)