In [15]: df = pd.DataFrame([1, 2, 3], index=[dt.datetime(2013, 1, 1), dt.datetime(2013, 1, 3), dt.datetime(2013, 1, 5)])
In [16]: df
Out[16]:
0
2013-01-01 1
2013-01-03 2
2013-01-05 3
In [22]: start = df.index.searchsorted(dt.datetime(2013, 1, 2))
In [23]: end = df.index.searchsorted(dt.datetime(2013, 1, 4))
In [24]: df.iloc[start:end]
Out[24]:
0
2013-01-03 2