df.query('D > B').query('C > B') # equivalent to # df.query('D > B and C > B') # but defeats the purpose of demonstrating chaining A B C D E 0 0 2 7 3 8 1 7 0 6 8 6 4 3 6 7 7 4 5 5 3 7 5 9 7 6 2 6 6 5