>>> import numpy as np >>> M = np.arange(10) >>> M array([0, 1, 2, 3, 4, 5, 6, 7, 8, 9]) >>> M[(M > 2) & (M < 7)] = -1 >>> M array([ 0, 1, 2, -1, -1, -1, -1, 7, 8, 9])