import requests
from requests_toolbelt.multipart.encoder import MultipartEncoder
m = MultipartEncoder({'roomId': 'Y2lzY2.....',
'text': 'example attached',
'files': ('example.png', open('example.png', 'rb'),
'image/png')})
r = requests.post('https://webexapis.com/v1/messages', data=m,
headers={'Authorization': 'Bearer ACCESS_TOKEN',
'Content-Type': m.content_type})
print r.text