since April of 2018 because Google decided to give greater control
of playback to users.
You just need to add &mute=1 to your URL.
<iframe
className="w-[95%] h-[80%] box-shadow"
src="https://www.youtube.com/embed/MkrNEj4RrbA?autoplay=1&mute=1"
title="YouTube video player"
frameborder="0"
allow="accelerometer;fullScreen; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture;"
allowFullScreen
></iframe>