<button type="button" class="btn btn-secondary" data-bs-toggle="tooltip" data-bs-html="true" title="<em>Tooltip</em> <u>with</u> <b>HTML</b>">
Tooltip with HTML
</button>
var exampleEl = document.getElementById('example')
var tooltip = new bootstrap.Tooltip(exampleEl, options)
<button type="button" class="btn btn-secondary" data-toggle="tooltip" data-placement="top" title="Tooltip on top">
Tooltip on top
</button>
<button type="button" class="btn btn-secondary" data-bs-toggle="tooltip" data-bs-placement="top" title="Tooltip on top">
Tooltip on top
</button>
<button type="button" class="btn btn-secondary" data-bs-toggle="tooltip" data-bs-placement="right" title="Tooltip on right">
Tooltip on right
</button>
<button type="button" class="btn btn-secondary" data-bs-toggle="tooltip" data-bs-placement="bottom" title="Tooltip on bottom">
Tooltip on bottom
</button>
<button type="button" class="btn btn-secondary" data-bs-toggle="tooltip" data-bs-placement="left" title="Tooltip on left">
Tooltip on left
</button>