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como filtrar los vacios, NaN, null en python

            method  number  orbital_period   mass  distance  year
0  Radial Velocity       1         269.300   7.10     77.40  2006
1  Radial Velocity       1         874.774   2.21     56.95  2008
2  Radial Velocity       1         763.000   2.60     19.84  2011
3  Radial Velocity       1         326.030  19.40    110.62  2007
4  Radial Velocity       1         516.220  10.50    119.47  2009
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