df = pd.DataFrame({'A':[61.75, 10.25], 'B':[0.62, 0.45]}) print (df) A B 0 61.75 0.62 1 10.25 0.45 df['A'] = df['A'].div(100).round(2) #same as #df['A'] = (df['A'] / 100).round(2) print (df) A B 0 0.62 0.62 1 0.10 0.45