import re
s = "Example String"
replaced = re.sub('[ES]', 'a', s)
print replaced
# will print 'axample atring'
import re
line = re.sub(r"</?[d+>", "", line)
# Comented version
line = re.sub(r"""
(?x) # Use free-spacing mode.
< # Match a literal '<'
/? # Optionally match a '/'
[ # Match a literal '['
d+ # Match one or more digits
> # Match a literal '>'
""", "", line)
result = re.sub(r"Pulp Fiction", "Forrest Gump", text)